Nail Involvement as a Predictor of Disease Severity in Paediatric Psoriasis: Follow-up Data from the Dutch ChildCAPTURE Registry

Authors

  • Inge M.G.J. Bronckers
  • Finola M. Bruins
  • Maartje J. van Geel
  • Hans M.M. Groenewoud
  • Wietske Kievit
  • Peter C.M. van de Kerkhof
  • Marcel C. Pasch
  • Elke M.G.J. de Jong
  • Marieke M.B. Seyger

DOI:

https://doi.org/10.2340/00015555-3036

Keywords:

paediatric psoriasis, pediatric psoriasis, nail psoriasis, psoriasis severity

Abstract

Little is known about the relationship between nail psoriasis and psoriasis severity in children, and there has been no longitudinal assessment of psoriasis severity related to nail psoriasis. The aim of this study was to assess whether nail psoriasis could serve as a predictor for a more severe disease course. De-identified data were obtained from the ChildCAPTURE registry, a daily clinical practice cohort of children with psoriasis, from September 2008 to November 2015. Cross-sectional analyses were performed at baseline. Longitudinal data until 2-year follow-up were analysed by linear mixed models. Nail psoriasis was present in 19.0% of all 343 patients at baseline and cross-sectionally associated with higher Psoriasis Area and Severity Index (PASI) (p?=?0.033). Longitudinal analysis demonstrated higher PASI (p?<?0.001) during 2-year follow-up in patients with nail involvement at baseline. These findings suggest that nail psoriasis is a potential clinical predictor for more severe disease course over time in paediatric psoriasis.

Downloads

Download data is not yet available.

Downloads

Published

2018-10-30

How to Cite

Bronckers, I. M., Bruins, F. M., van Geel, M. J., Groenewoud, H. M., Kievit, W., van de Kerkhof, P. C., … Seyger, M. M. (2018). Nail Involvement as a Predictor of Disease Severity in Paediatric Psoriasis: Follow-up Data from the Dutch ChildCAPTURE Registry. Acta Dermato-Venereologica, 99(2), 152–157. https://doi.org/10.2340/00015555-3036

Issue

Vol. 99 No. 2 (2019): February

Section

Articles

License

Copyright (c) 2018 Inge M.G.J. Bronckers, Finola M. Bruins, Maartje J. van Geel, Hans M.M. Groenewoud, Wietske Kievit, Peter C.M. van de Kerkhof, Marcel C. Pasch, Elke M.G.J. de Jong, Marieke M.B. Seyger

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.

Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.

Crossref
Scopus
Google Scholar
Europe PMC