Kaposi Sarcoma with Mucocutaneous Involvement in French Guiana: An Epidemiological Study between 1969 and 2019

Authors

  • Carl Lamoureux Department of Dermatology, Andrée-Rosemon Hospital, Cayenne, French Guiana
  • Kinan Drak Alsibai Department of Histopathology and Cytology, Andrée-Rosemon Hospital, Cayenne, French Guiana
  • Roger Pradinaud rogerpradinaud@orange.fr
  • Dominique Sainte-Marie dominique.sainte-marie@orange.fr
  • Pierre Couppie Department of Dermatology, Andrée-Rosemon Hospital, Cayenne, French Guiana
  • Romain Blaizot Dermatology Department, Andrée-Rosemon Hospital, Avenue des Flamboyants, 97300 Cayenne, French Guiana

DOI:

https://doi.org/10.2340/actadv.v102.581

Keywords:

Kaposi sarcoma, HHV8, Amerindians, Epidemiology, HIV, French Guiana

Abstract

Data on Kaposi sarcoma in French Guiana are scarce and out of date. This territory presents unique epidemiological features. The objectives of this retrospective study were to analyse the clinical features, outcome and incidence of the different forms of Kaposi sarcoma in patients diagnosed between 1969 and 2019. The study population comprised a total of 52 patients. Clinical forms included epidemic Kaposi sarcoma (n=30), endemic (n=18), iatrogenic (n=2), classic (n=1) and unclassified Kaposi sarcoma (n=1). The mean annual incidence rate of epidemic Kaposi reached a peak in the 1990s (0.93/100,000) then decreased in the 2000s (0.33/100,000), while the incidence of endemic Kaposi sarcoma reached a peak in the 1980s (0.82/100,000) before decreasing in the 2000s (0.12/100,000). Factors associated with the epidemic form were: sexual intercourse between men (p=0.0054) and Haitian origin (p=0.035). The presence of nodules and/or tumour, lesions limited to the lower limbs, and age >65 years were associated with the endemic form. While Creole populations seem to be as affected by endemic Kaposi sarcoma as their African counterparts, the dynamics of Kaposi sarcoma in French Guiana are now dominated by the epidemic form.

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Published

2022-05-10

How to Cite

Lamoureux, C., Drak Alsibai, K., Pradinaud, R., Sainte-Marie, D., Couppie, P., & Blaizot, R. (2022). Kaposi Sarcoma with Mucocutaneous Involvement in French Guiana: An Epidemiological Study between 1969 and 2019. Acta Dermato-Venereologica, 102, adv00709. https://doi.org/10.2340/actadv.v102.581