Bowen’s Disease: A Six-year Retrospective Study of Treatment with Emphasis on Resection Margins
DOI:
https://doi.org/10.2340/00015555-1771Keywords:
Bowen�s disease, squamous cell carcinoma in situ, surgical excision, safety margin.Abstract
Bowen’s disease is an in situ squamous cell carcinoma of the skin with various treatment modalities available. A major advantage of surgical excision is the opportunity to histologically examine the resection margins. There is no consensus about the most appropriate margin. This retrospective study evaluates the clearance rates achieved by excision with a 5 mm margin and estimates how that might change after fictitiously reducing the resection margin by 1 or 2 mm. Patients with histologically confirmed Bowen’s disease were selected at the Maastricht University Medical Centre from 2002 until 2007. Surgical margins and complete excision rates were evaluated and histological slides were re-examined. To our knowledge this is the first study investigating the safety margin for Bowen’s disease. As Bowen’s disease is not an invasive disease, minimisation of healthy tissue excision is desirable. Our data show that a hypothetical reduction of the safety margin from 5 mm to 4 or 3 mm decreases the complete excision rate from 94.4% to 87% and 74.1%, respectively.Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2013 Annet Westers-Attema, Fleur van den Heijkant, Bjorn G.P.M. Lohman, Patty J. Nelemans, Veronique Winnepenninckx, Nicole W.J. Kelleners-Smeets, Klara Mosterd
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All digitalized ActaDV contents is available freely online. The Society for Publication of Acta Dermato-Venereologica owns the copyright for all material published until volume 88 (2008) and as from volume 89 (2009) the journal has been published fully Open Access, meaning the authors retain copyright to their work.
Unless otherwise specified, all Open Access articles are published under CC-BY-NC licences, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material for non-commercial purposes, provided proper attribution to the original work.