Atopic Dermatitis and Essential Fatty Acids: a Biochemical Basis for Atopy?
DOI:
https://doi.org/10.2340/00015555114143145Abstract
The effects of dietary supplementation with evening primrose oil (Efamol) in 99 patients with atopic dermatitis were investigated in a double blind, controlled crossover study. Simultaneously, plasma phospholipid essential fatty acid status was determined in 50 of these patients before and after treatment. In a separate study, lymphocyte subsets and mitogen responses were investigated in 15 atopic patients before and after treatment. The conclusion is that evening primrose oil improves atopic dermatitis,an abnormality of the enzyme delta-6-desaturase is proposed to explain the biochemical findings. Finally,it is concluded that the therapeutic effect of evening primrose oil is unlikely to be mediated through a primarily immunological mechanism."Downloads
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Published
2020-12-09
How to Cite
Wright, S. (2020). Atopic Dermatitis and Essential Fatty Acids: a Biochemical Basis for Atopy?. Acta Dermato-Venereologica, 65(114), 143–145. https://doi.org/10.2340/00015555114143145
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