A Novel Case of Gorlin Syndrome Mosaicism Involving an SMO Gene Mutation: Clinical, Histological and Molecular Analysis of Basaloid Tumours

Authors

  • Meriem Ighilahriz
  • Sergey Nikolaev
  • Andrey A. Yurchenko
  • Maxime Battistella
  • Samia Mourah
  • Fanélie Jouenne
  • Emanuelle Bourrat
  • Nicole Basset-Seguin Department of Dermatology, Hôpital Saint Louis, FR-75010 Paris, France

DOI:

https://doi.org/10.2340/00015555-3797

Keywords:

Gorlin, mosaicism, SMO gene

Abstract

Abstract is missing (Short communication)

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References

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DOI: https://doi.org/10.1056/NEJM196005052621803

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DOI: https://doi.org/10.1016/S0092-8674(00)81268-4

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DOI: https://doi.org/10.1111/bjd.14425

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DOI: https://doi.org/10.1111/j.1365-2133.2005.06353.x

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DOI: https://doi.org/10.1183/13993003.01190-2019

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DOI: https://doi.org/10.1038/ng.3525

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Lovgren M-L, Zhou Y, Hr?ková G, Dallos T, Colmenero I, Twigg SRF, et al. Happle-Tinschert, Curry-Jones and segmental basal cell naevus syndromes, overlapping disorders caused by somatic mutations in hedgehog signalling genes: the mosaic hedgehog spectrum. Br J Dermatol 2020; 182: 212-217.

DOI: https://doi.org/10.1111/bjd.18150

Reinders MGHC, Boersma HJ, Leter EM, Vreeburg M, Paulussen ADC, Arits AHMM, et al. Postzygotic mosaicism in basal cell naevus syndrome. Br J Dermatol 2017; 177: 249-252.

DOI: https://doi.org/10.1111/bjd.15082

Sharpe HJ, Pau G, Dijkgraaf GJ, Basset-Seguin N, Modrusan Z, Januario T, et al. Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma. Cancer Cell 2015; 27: 327-341.

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DOI: https://doi.org/10.1093/emboj/cdg271

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Published

2021-04-22

How to Cite

Ighilahriz, M., Nikolaev, S., Yurchenko, A. A., Battistella, M., Mourah, S., Jouenne, F., Bourrat, E., & Basset-Seguin, N. (2021). A Novel Case of Gorlin Syndrome Mosaicism Involving an SMO Gene Mutation: Clinical, Histological and Molecular Analysis of Basaloid Tumours. Acta Dermato-Venereologica, 101(4), adv00434. https://doi.org/10.2340/00015555-3797

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