Small-fibre Neuropathy in Patients with Type 2 Diabetes Mellitus and its Relationship with Diabetic Itch: Preliminary Results

Authors

  • Aleksandra A. Stefaniak
  • Konstantin Agelopoulos
  • Dorota Bednarska-Chabowska
  • Grzegorz Mazur
  • Sonja Ständer
  • Jacek C. Szepietowski Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Chałubińskiego 1, PL-50-368 Wrocław, Poland

DOI:

https://doi.org/10.2340/actadv.v102.933

Keywords:

itch, neuron, small fibre neuropathy, IENFD, diabetes mellitus

Abstract

Abstract is missing (Short communication)

Downloads

Download data is not yet available.

References

Cho NH, Shaw JE, Karuranga S, Huang Y, da Rocha Fernandes JD, Ohlrogge AW, et al. IDF diabetes atlas: global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res Clin Pract 2018; 138: 271-281.

https://doi.org/10.1016/j.diabres.2018.02.023

Johannsen L, Smith T, Havsager AM, Madsen C, Kjeldsen MJ, Dalsgaard NJ, et al. Evaluation of patients with symptoms suggestive of chronic polyneuropathy. J Clin Neuromuscul Dis 2001; 3: 47-52.

https://doi.org/10.1097/00131402-200112000-00001

Pereira MP, Wiegmann H, Agelopoulos K, Ständer S. Neuropathic itch: routes to clinical diagnosis. Front Med 2021; 8: 641746.

https://doi.org/10.3389/fmed.2021.641746

Ständer S, Streit M, Darsow U, Niemeier V, Vogelgsang M, Ständer H, et al. Diagnostisches und therapeutisches Vorgehen beichronischem Pruritus. J Dtsch Dermatol Ges 2006; 4: 350-370.

https://doi.org/10.1111/j.1610-0387.2006.05887.x

Ständer S, Weisshaar E, Mettang T, Szepietowski J, Carstens E, Ikoma A, et al. Clinical classification of itch: a position paper of the International Forum for the Study of Itch. Acta Derm Venereol 2007; 87: 291-294.

https://doi.org/10.2340/00015555-0305

Pereira MP, Derichs L, Meyer Zu Hörste G, Agelopoulos K, Ständer S. Generalized chronic itch induced by small-fibre neuropathy: clinical profile and proposed diagnostic criteria. J Eur Acad Dermatol Venereol 2020; 34: 1795-1802.

https://doi.org/10.1111/jdv.16151

Brenaut E, Marcorelles P, Genestet S, Ménard D, Misery L. Pruritus: an underrecognized symptom of small-fibre neuropathies. J Am Acad Dermatol 2015; 72: 328-332.

https://doi.org/10.1016/j.jaad.2014.10.034

Bonsang B, Brenaut E, Talagas M, Uguen A, Bonsang-Kitzis H, Misery L, et al. Small-fibre neuropathy and pruritus: histological patterns of nerve fibres in skin biopsies. Br J Dermatol 2020: 182: 504-506.

https://doi.org/10.1111/bjd.18485

Akabane AL, Smith GP. Cutaneous manifestations of small fibre polyneuropathy. J Eur Acad Dermatology Venereol 2022; 36: 100-107.

https://doi.org/10.1111/jdv.17714

Stefaniak A, Chlebicka I, Szepietowski J. Itch in diabetes: a common underestimated problem. Adv Dermatol Allergol 2019; 36: 177-183.

https://doi.org/10.5114/ada.2019.89712

Stefaniak AA, Zubkiewicz-Kucharska A, Matusiak Ł, Noczyńska A, Szepietowski JC. Itch in children with type 1 diabetes: a cross-sectional study. Dermatol Ther 2020; 10: 745-756.

https://doi.org/10.1007/s13555-020-00403-w

Provitera V, Gibbons CH, Wendelschafer-Crabb G, Donadio V, Vitale DF, Stancanelli A, et al. A multi-center, multinational age- and gender-adjusted normative dataset for immunofluorescent intraepidermal nerve fibre density at the distal leg. Eur J Neurol 2016; 23: 333-338.

https://doi.org/10.1111/ene.12842

Stefaniak AA, Krajewski PK, Bednarska-Chabowska D, Bolanowski M, Mazur G, Szepietowski JC, et al. Itch in adult population with type 2 diabetes mellitus: clinical profile, pathogenesis and disease-related burden in a cross-sectional study. Biology 2021; 10: 1332.

https://doi.org/10.3390/biology10121332

Downloads

Published

2022-05-19

How to Cite

Stefaniak, A. A., Agelopoulos, K., Bednarska-Chabowska, D., Mazur, G., Ständer, S., & Szepietowski, J. C. (2022). Small-fibre Neuropathy in Patients with Type 2 Diabetes Mellitus and its Relationship with Diabetic Itch: Preliminary Results. Acta Dermato-Venereologica, 102, adv00719. https://doi.org/10.2340/actadv.v102.933