5-hydroxydopa, a new compound in the Raper-Mason scheme of melanogenesis

Authors

  • C. Hansson
  • H. Rorsman
  • E. Rosengren

DOI:

https://doi.org/10.2340/0001555560281286

Abstract

Oxidation of tyrosine or dopa by tyrosinase leads to the formation of 5-OH-dopa, a compound previously unknown in melanogenesis. 5-OH-dopa, first detected as an unknown compound on HPLC of the dopa-tyrosinase incubate, was purified by Al2O3-adsorption, semipreparative HPLC, and ion-exchange chromatography. 5-OH-dopa was identified by comparison with the authentic compound in several chromatographic systems, by electrochemical oxidation studies and by mass spectrometry.

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Published

1980-07-07

How to Cite

Hansson, C., Rorsman, H., & Rosengren, E. (1980). 5-hydroxydopa, a new compound in the Raper-Mason scheme of melanogenesis. Acta Dermato-Venereologica, 60(4), 281–286. https://doi.org/10.2340/0001555560281286

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Section

Articles