Societal Costs of Moderate-to-severe Atopic Dermatitis Occurring in Adulthood: A Danish Register-based Study

Authors

  • Jacob P. Thyssen
  • Andreas W. Brenneche Market Access; Nordics, LEO Pharma AB, 201 24 Malmö, Sweden
  • Maria E. Madsen
  • Mikkel H. Pedersen
  • Dennis J. Trangbaek
  • Christian Vestergaard

DOI:

https://doi.org/10.2340/00015555-3908

Keywords:

atopic dermatitis, burden of disease, cost of illness, real-world evidence, register-based cohort study

Abstract

To estimate the cost of illness in adult patients with moderate-to-severe atopic dermatitis (AD) a cohort study was conducted identifying Danish citizens (≥ 18 years) diagnosed with AD between 1997 and 2018 in the Danish National Patient Register. Moderate-to-severe AD was defined as ≥3 hospital contacts regarding AD the first year after  diagnosis. Each patient with AD was matched to 3 reference individuals through the Central Person Registry. Societal costs included the direct costs for primary-sector visits, inpatient hospitalizations, outpatient contacts, prescription medicine and indirect costs of lost productivity 3 years before and 5 years after the index date (the study period). A total of 5,245 patients with moderate-to-severe AD were identified. The mean attributable healthcare costs for patients with moderate-to-severe AD were EUR 10,835 (p < 0.0001) during the study period. Moderate-to-severe AD among adults inferred substantial economic burden compared with a group of matched reference individuals.

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Additional Files

Published

2021-09-03

How to Cite

Thyssen, J. P., Brenneche, . A. W., Madsen, M. E., Pedersen, M. H., Trangbaek, D. J., & Vestergaard, C. (2021). Societal Costs of Moderate-to-severe Atopic Dermatitis Occurring in Adulthood: A Danish Register-based Study. Acta Dermato-Venereologica, 101(9), adv00538. https://doi.org/10.2340/00015555-3908